Terrestrial Ecotoxicology and Disease Research Facility Core Technology Team
About the Research
The Terrestrial Ecotoxicology and Disease Research Facility Core Technology Team (CTT) as part of the Environmental Health Program provides an integrated mechanism for conducting controlled exposure studies on wildlife at varied spatiotemporal scales.

The Terrestrial Ecotoxicology and Disease Research CTT has three main research mechanisms:
- Captive bird colonies that can be used as models for various species of wild birds to address specific toxicological, disease or ecological hypotheses or questions;
- A variety of facilities to conduct these studies; and
- Laboratories that support this research by providing data on various non-apical genomic-molecular and biochemical indicators.
Bird Colonies
- The CTT research colonies are available for use in various types of toxicological, ecological and disease studies, including short-term exposures, reproductive and multigenerational studies, immune-challenge and disease resistance research.
- Current species include American Kestrel, Japanese quail (an avian model species for endocrine research) and several seaduck species. All of these species reproduce in captivity and are well-accepted research models used in wildlife toxicology.
Facilites

- Raptor facility which maintains kestrels in a series of large flight pens that have enabled the colony to reproduce and remain self-sustaining for over 50 years
- Smaller pens used for more controlled exposure studies, such as PFAS impacts on avian reproduction and physiological responses to pesticides
- Seaduck facility which include large pens with flow through water systems that provide clean filtered water to the ducks in a covered, outdoor setting
- Indoor diving tanks that serve as experimental chambers in which the birds’ diving behavior can be studied under various environmental conditions
- Mesocosms, each with its own pump house and wetland/marsh area that provides habitat for an entire food chain from invertebrates to amphibians, to birds
- Indoor experimental animal facilities, which permit temperature-controlled studies to be conducted
- Egg incubators can be used to hatch bird eggs whether collected from our own colonies or brought in from the field
- Two environmental chambers that provide for controlled temperature and light conditions used for reptile and amphibian exposures
Laboratories for Biomarker Analyses
- Fully equipped laboratory that provides gene expression, microbiome, antibiotic resistance and virulome analyses, along with other molecular methods
- Immune and chromogenic assays to analyze various biochemical indicators including those for oxidative stress, steroid and thyroid hormones
- Blood clotting assays and analyze for various response endpoints from both arms of the immune system.
Environmental Health Integrated Science Team Collaborators
-
Food Resources Lifecycle Integrated Science Team
The team studies the movement of toxicants and pathogens that could originate from the growing, raising, and processing/manufacturing of plant and animal products through the environment where exposure can occur. This information is used to understand if there are adverse effects upon exposure and to develop decision tools to protect health.Energy Resources Life Cycle Integrated Science Team
The Energy Resources Life Cycle Integrated Science Team focuses on the potential for environmental contaminant exposures that might originate from energy resource activities including extraction, production, transportation, storage, waste management, and restoration. Perceived health risks to humans and other organisms will be distinguished from actual risks, if any. If actual risks are identified...
Data related to the Terrestrial Ecotoxicology and Disease Research Facility CTT can be found below.
Scientific publications related to the Terrestrial Ecotoxicology and Disease Research Facility CTT can be found below.
Exposure to crop production alters cecal prokaryotic microbiota, inflates virulome and resistome in wild prairie grouse
Observations on Whooping Crane parental provisioning of chicks
Effects of low pH on the coral reef cryptic invertebrate communities near CO2 vents in Papua New Guinea
Establishment of baseline cytology metrics in nestling American kestrels (Falco sparverius): Immunomodulatory effects of the flame retardant isopropylated triarylphosphate isomers
A comparison of methods for the long-term harness-based attachment of radio-transmitters to juvenile Japanese quail (Coturnix japonica)
Global drivers of avian haemosporidian infections vary across zoogeographical regions
Sex- and developmental stage-related differences in the hepatic transcriptome of Japanese quail (Coturnix japonica) exposed to 17β-Trenbolone
Low MSP-1 haplotype diversity in the West Palearctic population of the avian malaria parasite Plasmodium relictum
The pathogenesis of a North American H5N2 clade 2.3.4.4 group A highly pathogenic avian influenza virus in surf scoters (Melanitta perspicillata)
Endocrine and physiological responses of hatchling American kestrels (Falco sparverius) following embryonic exposure to technical short-chain chlorinated paraffins (C10-13)
Minimizing the spread of aquatic herpetofaunal pathogens by decontaminating construction equipment
Robust geographical determinants of infection prevalence and a contrasting latitudinal diversity gradient for haemosporidian parasites in Western Palearctic birds
Connect with members of the Terrestrial Ecotoxicology and Disease Research Facility CTT below.
Alicia Berlin, Ph.D.
Research Wildlife Biologist
Serguei Drovetski, Ph.D.
Research Wildlife Biologist
Carlyn Caldwell
Biological Science Technician
Howard Ginsberg, Ph.D. (Former Employee)
Scientist Emeritus
Sharon Johnson
Supervisory Biological Science Technician
Glenn Olsen, Ph.D.
Veterinary Medical Officer
External partners that the Terrestrial Ecotoxicology and Disease Research Facility CTT collaborates with are linked below.
About the Research
The Terrestrial Ecotoxicology and Disease Research Facility Core Technology Team (CTT) as part of the Environmental Health Program provides an integrated mechanism for conducting controlled exposure studies on wildlife at varied spatiotemporal scales.

The Terrestrial Ecotoxicology and Disease Research CTT has three main research mechanisms:
- Captive bird colonies that can be used as models for various species of wild birds to address specific toxicological, disease or ecological hypotheses or questions;
- A variety of facilities to conduct these studies; and
- Laboratories that support this research by providing data on various non-apical genomic-molecular and biochemical indicators.
Bird Colonies
- The CTT research colonies are available for use in various types of toxicological, ecological and disease studies, including short-term exposures, reproductive and multigenerational studies, immune-challenge and disease resistance research.
- Current species include American Kestrel, Japanese quail (an avian model species for endocrine research) and several seaduck species. All of these species reproduce in captivity and are well-accepted research models used in wildlife toxicology.
Facilites

- Raptor facility which maintains kestrels in a series of large flight pens that have enabled the colony to reproduce and remain self-sustaining for over 50 years
- Smaller pens used for more controlled exposure studies, such as PFAS impacts on avian reproduction and physiological responses to pesticides
- Seaduck facility which include large pens with flow through water systems that provide clean filtered water to the ducks in a covered, outdoor setting
- Indoor diving tanks that serve as experimental chambers in which the birds’ diving behavior can be studied under various environmental conditions
- Mesocosms, each with its own pump house and wetland/marsh area that provides habitat for an entire food chain from invertebrates to amphibians, to birds
- Indoor experimental animal facilities, which permit temperature-controlled studies to be conducted
- Egg incubators can be used to hatch bird eggs whether collected from our own colonies or brought in from the field
- Two environmental chambers that provide for controlled temperature and light conditions used for reptile and amphibian exposures
Laboratories for Biomarker Analyses
- Fully equipped laboratory that provides gene expression, microbiome, antibiotic resistance and virulome analyses, along with other molecular methods
- Immune and chromogenic assays to analyze various biochemical indicators including those for oxidative stress, steroid and thyroid hormones
- Blood clotting assays and analyze for various response endpoints from both arms of the immune system.
Environmental Health Integrated Science Team Collaborators
-
Food Resources Lifecycle Integrated Science Team
The team studies the movement of toxicants and pathogens that could originate from the growing, raising, and processing/manufacturing of plant and animal products through the environment where exposure can occur. This information is used to understand if there are adverse effects upon exposure and to develop decision tools to protect health.Energy Resources Life Cycle Integrated Science Team
The Energy Resources Life Cycle Integrated Science Team focuses on the potential for environmental contaminant exposures that might originate from energy resource activities including extraction, production, transportation, storage, waste management, and restoration. Perceived health risks to humans and other organisms will be distinguished from actual risks, if any. If actual risks are identified...
Data related to the Terrestrial Ecotoxicology and Disease Research Facility CTT can be found below.
Scientific publications related to the Terrestrial Ecotoxicology and Disease Research Facility CTT can be found below.
Exposure to crop production alters cecal prokaryotic microbiota, inflates virulome and resistome in wild prairie grouse
Observations on Whooping Crane parental provisioning of chicks
Effects of low pH on the coral reef cryptic invertebrate communities near CO2 vents in Papua New Guinea
Establishment of baseline cytology metrics in nestling American kestrels (Falco sparverius): Immunomodulatory effects of the flame retardant isopropylated triarylphosphate isomers
A comparison of methods for the long-term harness-based attachment of radio-transmitters to juvenile Japanese quail (Coturnix japonica)
Global drivers of avian haemosporidian infections vary across zoogeographical regions
Sex- and developmental stage-related differences in the hepatic transcriptome of Japanese quail (Coturnix japonica) exposed to 17β-Trenbolone
Low MSP-1 haplotype diversity in the West Palearctic population of the avian malaria parasite Plasmodium relictum
The pathogenesis of a North American H5N2 clade 2.3.4.4 group A highly pathogenic avian influenza virus in surf scoters (Melanitta perspicillata)
Endocrine and physiological responses of hatchling American kestrels (Falco sparverius) following embryonic exposure to technical short-chain chlorinated paraffins (C10-13)
Minimizing the spread of aquatic herpetofaunal pathogens by decontaminating construction equipment
Robust geographical determinants of infection prevalence and a contrasting latitudinal diversity gradient for haemosporidian parasites in Western Palearctic birds
Connect with members of the Terrestrial Ecotoxicology and Disease Research Facility CTT below.
Alicia Berlin, Ph.D.
Research Wildlife Biologist
Serguei Drovetski, Ph.D.
Research Wildlife Biologist
Carlyn Caldwell
Biological Science Technician
Howard Ginsberg, Ph.D. (Former Employee)
Scientist Emeritus
Sharon Johnson
Supervisory Biological Science Technician
Glenn Olsen, Ph.D.
Veterinary Medical Officer
External partners that the Terrestrial Ecotoxicology and Disease Research Facility CTT collaborates with are linked below.